| General summary/purpose: The Division of Hematology is seeking a well-qualified, driven Laboratory Manager to work under the directions of Dr. Linda Resar. We are looking for someone who will serve as the lynchpin for the day-to-day operations of the lab, in addition to supporting the diverse research projects – and even running their own! We expect this person to serve as a liaison between the lab members and JHU departments and to help navigate the many complexities of running a research lab. The Laboratory Manager will be expected to be proficient in a large repertoire of research techniques that will allow them to work in both an independent manner as well as part of a collaborative team within the laboratory and also with collaborators at JHU and other institutions. He/she will play a vital role in various aspects of managing the laboratory Specific duties & responsibilities: Overall: Develop, design and manage substantial research projects, coordinates own objectives and those of laboratory team members. Supervise data collection and verification based on specialized skill and knowledge. Manage staff including recommendations for hiring, terminating and performance appraisal of a unit. Approve significant grant expenditures and approve significant equipment purchases. Implement new protocols, oversee assay validations in conjunction with PI. Responsible for overall operational elements of laboratory functioning as representative of PI. Design concept for computer databases to appropriately track and analyze results. Detailed Skills: - Manage the budget and spending oversight for the lab – including placing orders for materials and supplies, negotiating with vendors, and cost analysis of research projects
- Administer lab safety programs and train and monitor laboratory members as needed to ensure compliance with all applicable regulations; Set environmental health and safety standards and policy.
- Manage and prepare laboratory for yearly inspections for biosafety and other regulatory review processes.
- Oversight of essential equipment and maintenance
- Oversee the mouse genotyping, breeding, and embryo/sperm freezing program for the laboratory to ensure efficient and cost-effective management of large mouse genetic program
- Supervise management of the laboratory plasmid and cell line inventories
- Supervise technicians, students and volunteers in a variety of laboratory procedures: train, assign tasks, assess productivity and approve electronic timesheets, recommend for hire and performance appraisal.
- Supervise technicians and assist with time management among lab members to maintain organization and smooth running of the lab
- Assign shared responsibilities to lab members
- Work independently on experiments of own design, decide how experiments should be set up, and proceed to reach end result. Then interpret the data and report on the findings to the PI.
- Assemble, test, calibrate, clean or make repairs to all laboratory equipment, including specialized, highly sensitive and unique equipment that requires a specialized knowledge/skill.
- Order laboratory animals, reagents, specialized primers, and other unique reagents for experiments based on grant guidelines and experimental data.
- Utilize discretion in budget preparation and forecasting. Track budget and grant expenditures, make sure they are charged appropriately and adhere to grant stipulations. Communicate with vendors, review costs, and choose the appropriate reagents for laboratory experiments. Work in conjunction with Budget Analyst to allow for sufficient funds to support the lab operations.
- Report detailed results in an organized weekly lab meeting.
- Interact with faculty, lab and administrative staff, students, post-doctoral fellows and outside vendors.
- Manage staff including recommending for hire and performance appraisal, as well as training new laboratory personnel, graduate students, and post-doctoral fellows in laboratory techniques. Receive calls after routine work hours from post-doctoral fellows with questions or lab emergencies.
- Responsible for overall operational elements of laboratory functioning as representative of PI.
- Manage substantial research projects, coordinate own objectives and those of laboratory members.
- Writes and assists PI with laboratory manuscripts
- Process human samples (blood, urine, buccal mucosa cells, PBMC, buffy coats) for clinical trial studies.
Minimum qualifications (mandatory): Bachelor's degree in biology, chemistry or related field. Preferred qualifications: - B.A. or B.S. in Biological or Natural Sciences
- Minimum 5 years related laboratory research, technician or laboratory management experience
- Extensive experience in Molecular Biology (e.g. RNAseq, molecular cloning, library construction, PCR, recombinant protein expression and purification) and mammalian cell culture (transfections, retroviral transductions, reporter assays) or mouse genetics (mouse breeding, genotyping, phenotyping by immunohistochemistry and FACS screening)
- Candidate must be self-motivated, energetic and able to work in a diverse laboratory environment
- Excellent organizational, communication, computer and record-keeping skills
- Experience with management of large and diverse mouse colonies is especially desired
Special knowledge, skills, and abilities: - Extensive experience in Molecular Biology (e.g. RNAseq, molecular cloning, library construction, PCR, recombinant protein expression and purification) and mammalian cell culture (transfections, retroviral transductions, reporter assays) or mouse genetics (mouse breeding, genotyping, phenotyping by immunohistochemistry and FACS screening)
- Organizational skills
Technical qualifications or specialized certifications: - Extensive experience in Molecular Biology (e.g. RNAseq, molecular cloning, library construction, PCR, recombinant protein expression and purification) and mammalian cell culture (transfections, retroviral transductions, reporter assays) or mouse genetics (mouse breeding, genotyping, phenotyping by immunohistochemistry and FACS screening)
Supervisory responsibility (indicate the number and type of persons supervised by incumbent): - Supervise technicians, students and volunteers in a variety of laboratory procedures: train, assign tasks, assess productivity and approve electronic timesheets, recommend for hire and performance appraisal.
- Supervise technicians and assist with time management among lab members to maintain organization and smooth running of the lab
- Assign shared responsibilities to lab members
Classified Title: Laboratory Manager
Working Title: Laboratory Manager
Role/Level/Range: ACRP/04/MD
Starting Salary Range: $52,495-$72,210
Employee group: Full Time
Schedule: M-F; 8:30am-5:00pm
Exempt Status: Exempt
Location: 04-MD:School of Medicine Campus
Department name: 10002811-SOM DOM Hematology
Personnel area: School of Medicine The successful candidate(s) for this position will be subject to a pre-employment background check. If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the HR Business Services Office at jhurecruitment@jhu.edu. For TTY users, call via Maryland Relay or dial 711. The following additional provisions may apply depending on which campus you will work. Your recruiter will advise accordingly. During the Influenza ("the flu") season, as a condition of employment, The Johns Hopkins Institutions require all employees who provide ongoing services to patients or work in patient care or clinical care areas to have an annual influenza vaccination or possess an approved medical or religious exception. Failure to meet this requirement may result in termination of employment. The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office. Equal Opportunity Employer
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