6000! That's the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. The Pre-Clinical Safety (PCS) group in NIBR provides world class preclinical safety profiling and assessment for optimal drug discovery, development and commercialization, with state-of-the-art regulatory compliance.

The Preclinical Safety team is seeking a Preclinical Safety Study Scientist. As a Preclinical Safety Study Scientist you will conducts in vivo non-GLP preclinical safety studies for Laboratory Sciences in various laboratory animal species as well as perform all the technical procedures (including formulations, dosing, in-life observations, and sample collection) necessary to implement and conduct study protocols for safety evaluation studies with minimal supervision.

Your responsibilities will include, but are not limited to:

* Perform technical procedures necessary to execute in vivo aspects of study protocols. These procedures may include formulation preparations, animal handling, dosing, weighing, and feeding, clinical observations, sample collection (biopsies, blood, urine, etc.), electronic data collection including telemetry.
* Display competence in the operation, calibration and troubleshooting of all laboratory instrumentation routinely employed. Assists in the maintenance of laboratory inventories and equipment. May assist in the validation of new methodologies and instrumentation as needed.
* Display competence in the use of Preclinical Safety electronic data collection system (PRISTIMA, emka); experience with Electronic Laboratory Notebooks (ELN) a plus.
* Know and conform to animal welfare regulations, Novartis working practices, IACUC policies, standards, requirements, and guidelines.
* May assist in methods development.
* May support in vivo technical procedures for other PCS studies on as needed basis
* Potential for cross-training in procedures necessary to execute postmortem (ex vivo) aspects of study protocols. These procedures may include necropsy, blood and tissue collection, handling and weighing laboratory animals, organ weighing, trimming, tissue-processing, paraffin/epoxy resin-embedding, preparing tissues for frozen sectioning, cryostat sectioning, microtomy, routine & special staining techniques, cover slipping, electron microscopy/digital imaging, x-ray spectrometry, light/fluorescence microscopy and QC activities