Vacancy ID: PDS003449Position Summary/Description: A postdoctoral research position is available immediately to investigate the utility of in vitro models (e.g., hepatic organoid 3D cell models, sandwich-cultured hepatocytes, HuH-7 cells, membrane vesicle systems) to (1) predict the hepatic disposition of drugs and metabolites in vivo, (2) predict the impact of disease-mediated alterations in transport function on hepatocellular accumulation and routes of excretion (canalicular vs. basolateral) of anionic drugs/metabolites, and (3) examine hepatic transporter trafficking and regulatory mechanisms.NIH-funded research program to study the hepatic disposition of xenobiotics utilizing in vitro model systems, reg